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Yohimbine
Yohimbine
Product Name: Yohimbine
CAS:146-48-5
Synonyms:
Yohimbin;Yocon;Yohimex;Corynine;Aphrosol;RAUBASIN;Aphrodine;yohimbine;Aphrodyne;Quebrachin
Yohimbine Properties
Melting point | 231-233 °C(lit.) |
alpha | D20 +50.9 to +62.2° (ethanol); D20 +108° (pyridine); 20546 +129° (c = 0.5 in pyridine) |
Boiling point | 487.66°C (rough estimate) |
Density | 1.1640 (rough estimate) |
refractive index | 1.6500 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | THF; DMSO; Chloroform; |
form | Solid |
pka | 14.39±0.40(Predicted) |
color | Beige |
Uses: Its derivatives areused therapeutically as adrenergic blockingagent, yohimbine works primarily by acting as an antagonist at α2-adrenergic receptors.
Clinical Use:
Yohimbine increases heart rate and blood pressure as aresult of its blockade of 2-receptors in the CNS. It has beenused experimentally to treat male erectile impotence.
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