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4-Piperidone
4-Piperidone
IUPAC Name: 4-Piperidone
CAS NO: 41661-47-6
Boiling point | 175.1±15.0 °C(Predicted) |
Density | 1.001±0.06 g/cm3(Predicted) |
pka | 8.95±0.20(Predicted) |
form | solid |
color | yellow |
Description
4-Piperidinone is a derivative of piperidine with the molecular formula C5H9NO. 4-Piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs.
Piperidones are a class of chemical compounds sharing the piperidone skeleton. A classic named reaction for the synthesis of piperidones is the Petrenko-Kritschenko piperidone synthesis which involves combining an alkyl-1,3-acetonedicarboxylate with benzaldehyde and an amine. This multicomponent reaction is related to the Hantzsch pyridine synthesis.
Uses
4-Piperidone monohydrate hydrochloride was used in the generation of compound libraries based on sub-reactions of an Ugi multicomponent reaction (MCR).
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